CMap Candidate Details

Structure:
CMap ID: C00544
Pert ID: BRD-A21584801
Compound Name: brivanib
Targets: FGFR1; FLT1; KDR
MoA: FGFR inhibitor; VEGFR inhibitor
SMILES: CC(O)COc1cn2ncnc(Oc3ccc4[nH]c(C)cc4c3F)c2c1C
InchiKey: WCWUXEGQKLTGDX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
92009 BRD-A21584801 A375 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.79 0.11
92051 BRD-A21584801 BT20 0.37 uM 3 h 0.27 1.14 0.32 0.0 0.0 0.0
92083 BRD-A21584801 HA1E 10 uM 24 h -0.2 -0.83 0.0 0.24 0.83 0.12
92120 BRD-A21584801 HCC515 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92173 BRD-A21584801 HS578T 0.04 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92203 BRD-A21584801 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92225 BRD-A21584801 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92266 BRD-A21584801 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92301 BRD-A21584801 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92356 BRD-A21584801 PC3 10 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.07
92398 BRD-A21584801 SKBR3 0.04 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).