CMap Candidate Details

Structure:
CMap ID: C05448
Pert ID: BRD-K09711437
Compound Name: varespladib
Targets: PLA2G2A
MoA: Secretory phospholipase inhibitor
SMILES: CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1
InchiKey: BHLXTPHDSZUFHR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121192 BRD-K09711437 A549 3.33 uM 24 h 0.27 1.14 0.32 0.0 0.0 0.0
121253 BRD-K09711437 HELA 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121320 BRD-K09711437 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129247 BRD-K09711437 A375 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129255 BRD-K09711437 HA1E 0.03 uM 24 h 0.0 0.0 0.0 -0.19 -0.64 0.01
129302 BRD-K09711437 HT29 0.03 uM 24 h -0.22 -0.93 0.07 -0.37 -1.24 1.3
129338 BRD-K09711437 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.36 1.26 1.29
129376 BRD-K09711437 YAPC 0.01 uM 24 h 0.0 0.0 0.0 -0.17 -0.58 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).