CMap Candidate Details

Structure:
CMap ID: C00546
Pert ID: BRD-A21607826
Compound Name: medetomidine
Targets: ADRA2A; ADRA2B; ADRA2C
MoA: Adrenergic receptor agonist
SMILES: CC(c1c[nH]cn1)c1cccc(C)c1C
InchiKey: CUHVIMMYOGQXCV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121388 BRD-A21607826 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121414 BRD-A21607826 HELA 10 uM 24 h 0.23 0.98 0.09 0.0 0.0 0.0
121465 BRD-A21607826 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.23 0.82 0.1
121520 BRD-A21607826 YAPC 1.11 uM 24 h 0.0 0.0 0.0 -0.3 -1.03 0.62
129408 BRD-A21607826 A375 0.74 uM 24 h -0.28 -1.16 0.45 0.0 0.0 0.0
129496 BRD-A21607826 HT29 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129558 BRD-A21607826 PC3 0.74 uM 24 h -0.31 -1.29 0.77 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).