CMap Candidate Details

Structure:
CMap ID: C00547
Pert ID: BRD-A21723284
Compound Name: naltriben
Targets: OPRD1
MoA: Opioid receptor antagonist
SMILES: Oc1ccc2CC3N(CC4CC4)CCC5(C6Oc1c25)C3(O)Cc7c6oc8ccccc78
InchiKey: ZHVWWEYETMPAMX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1485 BRD-A21723284 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1814 BRD-A21723284 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2324 BRD-A21723284 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2562 BRD-A21723284 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41652 BRD-A21723284 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42001 BRD-A21723284 A549 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.23 1.25
42185 BRD-A21723284 ASC 10 uM 24 h -0.33 -1.37 1.08 0.0 0.0 0.0
42530 BRD-A21723284 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.39 1.38 2.17
42838 BRD-A21723284 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43115 BRD-A21723284 MCF??7.00 10 uM 24 h 0.24 0.98 0.09 0.0 0.0 0.0
43385 BRD-A21723284 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43998 BRD-A21723284 SKB 10 uM 24 h 0.23 0.97 0.08 0.31 1.09 0.67
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).