CMap Candidate Details

Structure:
CMap ID: C05473
Pert ID: BRD-K09790412
Compound Name: H-9
Targets: PRKACA
MoA: PKA inhibitor
SMILES: NCCNCc1cccc2cnccc12
InchiKey: YVVIHNCTCNPFJM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
33673 BRD-K09790412 A375 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.06 0.73
34043 BRD-K09790412 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34311 BRD-K09790412 HA1E 10 uM 6 h -0.19 -0.8 0.0 0.2 0.7 0.02
34558 BRD-K09790412 HCC515 10 uM 6 h -0.21 -0.88 0.03 -0.23 -0.76 0.07
34826 BRD-K09790412 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.2
35092 BRD-K09790412 HT29 10 uM 6 h -0.21 -0.86 0.02 0.0 0.0 0.0
35448 BRD-K09790412 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
35539 BRD-K09790412 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
35728 BRD-K09790412 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36061 BRD-K09790412 PC3 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.0 0.52
36202 BRD-K09790412 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36495 BRD-K09790412 SKB 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.85
36775 BRD-K09790412 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96111 BRD-K09790412 A549 10 uM 24 h -0.23 -0.97 0.1 -0.3 -1.02 0.59
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).