CMap Candidate Details

Structure:
CMap ID: C00055
Pert ID: BRD-A02180903
Compound Name: betamethasone
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: C[C@H]1CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
InchiKey: UREBDLICKHMUKA-REKGUKDCSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5246 BRD-A02180903 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.14 1.03
5709 BRD-A02180903 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.29 1.53
5814 BRD-A02180903 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.79 0.11
6229 BRD-A02180903 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6339 BRD-A02180903 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37035 BRD-A02180903 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37209 BRD-A02180903 A549 10 uM 24 h -0.22 -0.93 0.07 -0.32 -1.06 0.74
37427 BRD-A02180903 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37972 BRD-A02180903 HT29 10 uM 6 h 0.0 0.0 0.0 0.3 1.08 0.65
38123 BRD-A02180903 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38281 BRD-A02180903 NPC 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.1
38592 BRD-A02180903 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).