CMap Candidate Details

Structure:
CMap ID: C05531
Pert ID: BRD-K09991945
Compound Name: BRD-K09991945
Targets: --
MoA: --
SMILES: Ic1cccc(CSc2nnc(o2)c3ccncc3)c1
InchiKey: ZRHRPGSSSVYBRG-UHFFFAOYSA-N
Compound Aliases: GSK-3-inhibitor-II

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6865 BRD-K09991945 A375 10 uM 6 h 0.23 0.95 0.06 0.0 0.0 0.0
7137 BRD-K09991945 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7424 BRD-K09991945 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7622 BRD-K09991945 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7986 BRD-K09991945 HT29 10 uM 6 h 0.31 1.28 0.61 0.0 0.0 0.0
8179 BRD-K09991945 MCF??7.00 10 uM 6 h 0.17 0.73 0.0 0.25 0.9 0.22
90294 BRD-K09991945 VCAP 12.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91534 BRD-K09991945 BT20 0.37 uM 6 h 0.0 0.0 0.0 -0.32 -1.08 0.78
91598 BRD-K09991945 HS578T 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91733 BRD-K09991945 SKBR3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92947 BRD-K09991945 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93016 BRD-K09991945 CD34 1.11 uM 24 h 0.26 1.09 0.23 0.33 1.15 0.9
93102 BRD-K09991945 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93143 BRD-K09991945 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93185 BRD-K09991945 HEPG2 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93242 BRD-K09991945 HUVEC 1.11 uM 24 h 0.27 1.12 0.26 -0.26 -0.88 0.25
93293 BRD-K09991945 JURKAT 10 uM 24 h 0.24 1.02 0.12 0.0 0.0 0.0
93329 BRD-K09991945 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.24
93371 BRD-K09991945 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93403 BRD-K09991945 NPC 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.35
93460 BRD-K09991945 PC3 0.04 uM 24 h 0.0 0.0 0.0 -0.3 -0.99 0.51
93497 BRD-K09991945 SKL 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93557 BRD-K09991945 THP1 0.37 uM 24 h -0.24 -1.0 0.15 -0.28 -0.95 0.4
93598 BRD-K09991945 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.73 0.04
99271 BRD-K09991945 U2OS 12.5 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).