CMap Candidate Details

Structure:
CMap ID: C05585
Pert ID: BRD-K10176267
Compound Name: L-701252
Targets: GRIN1
MoA: Glutamate receptor antagonist
SMILES: Oc1c(C(=O)C2CC2)c(=O)[nH]c2cc(Cl)ccc12
InchiKey: MXEFWCFPCLDOOG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2984 BRD-K10176267 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3140 BRD-K10176267 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3595 BRD-K10176267 PC3 10 uM 6 h 0.0 0.0 0.0 0.34 1.19 1.01
3941 BRD-K10176267 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41720 BRD-K10176267 A375 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.14
42058 BRD-K10176267 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42927 BRD-K10176267 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43158 BRD-K10176267 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43484 BRD-K10176267 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100063 BRD-K10176267 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).