CMap Candidate Details

Structure:
CMap ID: C05597
Pert ID: BRD-K10207760
Compound Name: lasalocid
Targets: --
MoA: --
SMILES: CC[C@H]([C@H]1O[C@@](CC)(C[C@@H]1C)[C@H]2CC[C@](O)(CC)[C@H](C)O2)C(=O)[C@@H](C)[C@@H](O)[C@H](C)CCc3ccc(C)c(O)c3C(=O)O
InchiKey: BBMULGJBVDDDNI-OWKLGTHSSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4057 BRD-K10207760 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4360 BRD-K10207760 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4646 BRD-K10207760 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5032 BRD-K10207760 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44301 BRD-K10207760 A375 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.87 0.23
44519 BRD-K10207760 A549 10 uM 24 h 0.2 0.85 0.01 0.0 0.0 0.0
44850 BRD-K10207760 ASC 10 uM 24 h 0.27 1.14 0.31 0.31 1.09 0.67
45159 BRD-K10207760 HEPG2 10 uM 6 h 0.22 0.93 0.05 0.0 0.0 0.0
45425 BRD-K10207760 HT29 10 uM 6 h 0.0 0.0 0.0 0.38 1.36 1.72
45649 BRD-K10207760 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45965 BRD-K10207760 NPC 10 uM 24 h 0.27 1.14 0.32 0.0 0.0 0.0
46285 BRD-K10207760 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46601 BRD-K10207760 SKB 10 uM 24 h 0.19 0.8 0.0 0.32 1.14 0.87
100064 BRD-K10207760 U2OS 3.33 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).