CMap Candidate Details

Structure:
CMap ID: C00561
Pert ID: BRD-A22256192
Compound Name: terazosin
Targets: ADRA1D; ADRA1B; ADRA1A
MoA: Adrenergic receptor antagonist
SMILES: COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1CCCO1
InchiKey: VCKUSRYTPJJLNI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
19209 BRD-A22256192 A549 10 uM 24 h 0.0 0.0 0.0 -0.19 -0.65 0.01
19542 BRD-A22256192 HA1E 10 uM 6 h 0.35 1.46 1.12 0.0 0.0 0.0
19862 BRD-A22256192 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20188 BRD-A22256192 HEPG2 10 uM 6 h 0.23 0.94 0.06 -0.36 -1.21 1.24
20525 BRD-A22256192 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21676 BRD-A22256192 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24372 BRD-A22256192 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25125 BRD-A22256192 PC3 10 uM 24 h 0.0 0.0 0.0 -0.18 -0.61 0.0
51557 BRD-A22256192 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91496 BRD-A22256192 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).