CMap Candidate Details

Structure:
CMap ID: C00564
Pert ID: BRD-A22305049
Compound Name: benfluorex
Targets: HMGCR
MoA: Gluconeogenesis inhibitor
SMILES: CC(Cc1cccc(c1)C(F)(F)F)NCCOC(=O)c1ccccc1
InchiKey: CJAVTWRYCDNHSM-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
51386 BRD-A22305049 PC3 10 uM 24 h 0.29 1.21 0.47 0.34 1.2 1.13
97603 BRD-A22305049 NKDBA 10 uM 24 h 0.18 0.76 0.0 0.37 1.3 1.58
121530 BRD-A22305049 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129413 BRD-A22305049 A375 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129448 BRD-A22305049 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129473 BRD-A22305049 HELA 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129499 BRD-A22305049 HT29 0.74 uM 24 h -0.27 -1.12 0.38 -0.39 -1.31 1.71
129530 BRD-A22305049 MCF??7.00 0.03 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).