CMap Candidate Details

Structure:
CMap ID: C05688
Pert ID: BRD-K10573841
Compound Name: tunicamycin
Targets: GNPTAB
MoA: GLCNAC phosphotransferase inhibitor
SMILES: CC(C)CCCCCCCCC=CC(=O)N[C@H]1[C@H](O[C@@H]2O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]2NC(C)=O)O[C@H](C[C@@H](O)[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2ccc(=O)[nH]c2=O)[C@H](O)[C@@H]1O
InchiKey: YJQCOFNZVFGCAF-WPTOCQRYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25622 BRD-K10573841 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26068 BRD-K10573841 A549 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.3 1.59
26260 BRD-K10573841 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
26600 BRD-K10573841 HA1E 10 uM 6 h -0.17 -0.72 0.0 0.0 0.0 0.0
26912 BRD-K10573841 HCC515 10 uM 6 h -0.24 -1.0 0.14 0.0 0.0 0.0
27220 BRD-K10573841 HT29 10 uM 6 h 0.0 0.0 0.0 -0.44 -1.48 15.35
27673 BRD-K10573841 MCF??7.00 10 uM 6 h -0.24 -1.0 0.15 0.0 0.0 0.0
27846 BRD-K10573841 NEU 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.73
28156 BRD-K10573841 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28446 BRD-K10573841 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28795 BRD-K10573841 PHH 10 uM 24 h 0.0 0.0 0.0 -0.42 -1.4 2.02
29111 BRD-K10573841 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29425 BRD-K10573841 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.76
90601 BRD-K10573841 HCT116 10 uM 24 h 0.0 0.0 0.0 0.19 0.69 0.01
90661 BRD-K10573841 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98085 BRD-K10573841 P1A82 3.33 uM 24 h 0.0 0.0 0.0 -0.29 -0.96 0.43
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).