CMap Candidate Details

Structure:
CMap ID: C00569
Pert ID: BRD-A22642447
Compound Name: licarbazepine
Targets: SCN5A
MoA: Voltage-gated sodium channel blocker
SMILES: NC(=O)N1c2ccccc2CC(O)c2ccccc12
InchiKey: BMPDWHIDQYTSHX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96354 BRD-A22642447 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96425 BRD-A22642447 PC3 1.11 uM 24 h -0.24 -1.0 0.14 0.0 0.0 0.0
121418 BRD-A22642447 HELA 0.04 uM 24 h 0.26 1.09 0.22 0.0 0.0 0.0
121445 BRD-A22642447 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121467 BRD-A22642447 MCF??7.00 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121528 BRD-A22642447 YAPC 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.89 0.26
129446 BRD-A22642447 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).