CMap Candidate Details

Structure:
CMap ID: C05707
Pert ID: BRD-K10649245
Compound Name: BRD-K10649245
Targets: --
MoA: --
SMILES: C[C@H](CO)N1C[C@H](C)[C@H](CN(C)Cc2ccc(cc2)C(=O)Nc3ccccc3N)Oc4c(NC(=O)Nc5ccccc5)cccc4C1=O
InchiKey: XHCFGJIATIGRMD-DVIHYUSWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
46862 BRD-K10649245 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
47184 BRD-K10649245 A549 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.34
47531 BRD-K10649245 HA1E 10 uM 6 h 0.16 0.68 0.0 0.0 0.0 0.0
47852 BRD-K10649245 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
48175 BRD-K10649245 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.95 0.41
48503 BRD-K10649245 HT29 10 uM 6 h 0.0 0.0 0.0 -0.37 -1.24 1.31
48806 BRD-K10649245 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
49255 BRD-K10649245 PC3 10 uM 6 h -0.23 -0.98 0.12 -0.32 -1.08 0.79
49457 BRD-K10649245 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).