CMap Candidate Details

Structure:
CMap ID: C00572
Pert ID: BRD-A22707317
Compound Name: SB-205384
Targets: GABRA3; GABRA5; GABRA6
MoA: GABA receptor modulator
SMILES: CC#CCOC(=O)c1c(C)nc2sc3CC(O)CCc3c2c1N
InchiKey: JDTZAGLGBRRCJT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1486 BRD-A22707317 HA1E 10 uM 24 h 0.0 0.0 0.0 0.26 0.92 0.25
1815 BRD-A22707317 HCC515 10 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.32
2594 BRD-A22707317 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42002 BRD-A22707317 A549 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.33 1.72
42186 BRD-A22707317 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42531 BRD-A22707317 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42839 BRD-A22707317 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43116 BRD-A22707317 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43386 BRD-A22707317 NPC 10 uM 24 h -0.2 -0.84 0.01 -0.27 -0.9 0.28
97172 BRD-A22707317 A375 10 uM 24 h 0.21 0.89 0.02 0.0 0.0 0.0
97234 BRD-A22707317 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.23 0.8 0.08
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).