CMap Candidate Details

Structure:
CMap ID: C00573
Pert ID: BRD-A22713669
Compound Name: BVT-948
Targets: PTPN1; PTPN2; PTPN11
MoA: Tyrosine phosphatase inhibitor
SMILES: CC1(C)C2C(=NC1=O)c3ccccc3C(=O)C2=O
InchiKey: AJVXVYTVAAWZAP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6625 BRD-A22713669 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6920 BRD-A22713669 A549 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
7516 BRD-A22713669 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7752 BRD-A22713669 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8042 BRD-A22713669 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.44 -1.47 15.35
8298 BRD-A22713669 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8748 BRD-A22713669 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.07 0.75
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).