CMap Candidate Details
Structure:
| CMap ID: | C05757 |
| Pert ID: | BRD-K10799896 |
| Compound Name: | clobetasol |
| Targets: | NR3C1 |
| MoA: | Glucocorticoid receptor agonist |
| SMILES: | CCC(=O)O[C@@]1([C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C)C(=O)CCl |
| InchiKey: | CBGUOGMQLZIXBE-XGQKBEPLSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 49810 | BRD-K10799896 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50152 | BRD-K10799896 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50339 | BRD-K10799896 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.26 | -0.88 | 0.24 |
| 50504 | BRD-K10799896 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 50654 | BRD-K10799896 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.34 | 1.2 | 1.13 |
| 50911 | BRD-K10799896 | PC3 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 51009 | BRD-K10799896 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |