CMap Candidate Details

Structure:
CMap ID: C00578
Pert ID: BRD-A22844106
Compound Name: tenoxicam
Targets: PTGS1; PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: CN1C(C(=O)Nc2ccccn2)C(=O)c2sccc2S1(=O)=O
InchiKey: OTGJPAOGHQFBMI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5258 BRD-A22844106 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5715 BRD-A22844106 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5831 BRD-A22844106 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.7 0.03
5975 BRD-A22844106 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6127 BRD-A22844106 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6457 BRD-A22844106 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39038 BRD-A22844106 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39267 BRD-A22844106 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39557 BRD-A22844106 ASC 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.76 0.07
40562 BRD-A22844106 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40689 BRD-A22844106 NEU 10 uM 24 h 0.0 0.0 0.0 -0.39 -1.31 1.69
40983 BRD-A22844106 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41306 BRD-A22844106 SKB 10 uM 24 h -0.31 -1.31 0.82 -0.36 -1.22 1.25
91494 BRD-A22844106 HUH7 10 uM 72 h -0.33 -1.38 1.08 -0.26 -0.87 0.24
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).