CMap Candidate Details

Structure:
CMap ID: C05787
Pert ID: BRD-K10860596
Compound Name: granisetron
Targets: HTR3A
MoA: Serotonin receptor antagonist
SMILES: CN1[C@H]2CCC[C@@H]1C[C@@H](C2)NC(=O)c3nn(C)c4ccccc34
InchiKey: MFWNKCLOYSRHCJ-BTTYYORXSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
22054 BRD-K10860596 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22243 BRD-K10860596 A549 10 uM 6 h 0.25 1.04 0.15 0.0 0.0 0.0
22432 BRD-K10860596 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22698 BRD-K10860596 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22981 BRD-K10860596 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.19
23288 BRD-K10860596 HT29 10 uM 6 h 0.0 0.0 0.0 0.19 0.67 0.01
23546 BRD-K10860596 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
23965 BRD-K10860596 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24283 BRD-K10860596 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91188 BRD-K10860596 HUH7 10 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).