CMap Candidate Details

Structure:
CMap ID: C00579
Pert ID: BRD-A22897758
Compound Name: pinacidil
Targets: ABCC9; ABCC8
MoA: ATP channel activator; Potassium channel activator
SMILES: CC(C(C)(C)C)N=C(/NC#N)Nc1ccncc1
InchiKey: IVVNZDGDKPTYHK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
21889 BRD-A22897758 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22198 BRD-A22897758 A549 10 uM 6 h -0.27 -1.14 0.42 0.22 0.79 0.08
22635 BRD-A22897758 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22915 BRD-A22897758 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.82 0.15
23221 BRD-A22897758 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23503 BRD-A22897758 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
23782 BRD-A22897758 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24075 BRD-A22897758 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).