CMap Candidate Details

Structure:
CMap ID: C05790
Pert ID: BRD-K10870738
Compound Name: CDC
Targets: ALOX12
MoA: Lipoxygenase inhibitor
SMILES: Oc1ccc(/C=C(/C#N)C(=O)OCC=Cc2ccccc2)cc1O
InchiKey: XGHYFEJMJXGPGN-CHLGNXTCSA-N
Compound Aliases: cdc

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1543 BRD-K10870738 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
1885 BRD-K10870738 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2373 BRD-K10870738 PC3 10 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
2542 BRD-K10870738 VCAP 10 uM 24 h 0.26 1.08 0.22 -0.32 -1.09 0.84
41722 BRD-K10870738 A375 10 uM 6 h 0.0 0.0 0.0 0.24 0.86 0.16
41908 BRD-K10870738 A549 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.15 1.06
42293 BRD-K10870738 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42626 BRD-K10870738 HEPG2 10 uM 6 h 0.29 1.22 0.48 0.0 0.0 0.0
42929 BRD-K10870738 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43291 BRD-K10870738 MCF??7.00 10 uM 6 h -0.22 -0.91 0.06 -0.22 -0.73 0.04
43486 BRD-K10870738 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43790 BRD-K10870738 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44067 BRD-K10870738 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).