CMap Candidate Details

Structure:
CMap ID: C05816
Pert ID: BRD-K10961822
Compound Name: latanoprost
Targets: PTGFR
MoA: Prostanoid receptor agonist
SMILES: CC(C)OC(=O)CCCC=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CC[C@@H](O)CCc1ccccc1
InchiKey: GGXICVAJURFBLW-CEYXHVGTSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25491 BRD-K10961822 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.39 -1.3 1.6
91078 BRD-K10961822 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
121166 BRD-K10961822 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121202 BRD-K10961822 A549 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121237 BRD-K10961822 HA1E 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121294 BRD-K10961822 MCF??7.00 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121329 BRD-K10961822 PC3 0.04 uM 24 h -0.21 -0.86 0.02 -0.42 -1.41 2.02
129282 BRD-K10961822 HELA 2.22 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
129316 BRD-K10961822 HT29 0.08 uM 24 h -0.22 -0.91 0.05 0.0 0.0 0.0
129387 BRD-K10961822 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).