CMap Candidate Details

Structure:
CMap ID: C00582
Pert ID: BRD-A23067620
Compound Name: itraconazole
Targets: --
MoA: --
SMILES: CCC(C)n1ncn(-c2ccc(cc2)N2CCN(CC2)c2ccc(OC[C@H]3CO[C@@](Cn4cncn4)(O3)c3ccc(Cl)cc3Cl)cc2)c1=O
InchiKey: VHVPQPYKVGDNFY-ZPGVKDDISA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121377 BRD-A23067620 A375 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.28 1.45
121392 BRD-A23067620 HA1E 10 uM 24 h -0.27 -1.14 0.43 -0.29 -0.97 0.46
121424 BRD-A23067620 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121489 BRD-A23067620 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121538 BRD-A23067620 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129505 BRD-A23067620 HT29 2.22 uM 24 h -0.23 -0.97 0.11 0.0 0.0 0.0
129537 BRD-A23067620 MCF??7.00 2.22 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.69
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).