CMap Candidate Details

Structure:
CMap ID: C00583
Pert ID: BRD-A23072235
Compound Name: pheniramine
Targets: HRH1
MoA: Histamine receptor antagonist
SMILES: CN(C)CCC(c1ccccc1)c1ccccn1
InchiKey: IJHNSHDBIRRJRN-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2799 BRD-A23072235 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3092 BRD-A23072235 HCC515 10 uM 24 h 0.31 1.29 0.67 0.0 0.0 0.0
3430 BRD-A23072235 PC3 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
3673 BRD-A23072235 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44236 BRD-A23072235 A375 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.6
44637 BRD-A23072235 A549 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.76 0.07
44752 BRD-A23072235 ASC 10 uM 24 h -0.22 -0.91 0.05 -0.35 -1.17 1.12
45073 BRD-A23072235 HEPG2 10 uM 6 h -0.28 -1.18 0.5 -0.42 -1.41 2.02
45352 BRD-A23072235 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45736 BRD-A23072235 MCF??7.00 10 uM 6 h 0.22 0.93 0.05 0.25 0.89 0.21
45873 BRD-A23072235 NPC 10 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
46185 BRD-A23072235 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46502 BRD-A23072235 SKB 10 uM 24 h 0.0 0.0 0.0 0.27 0.97 0.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).