CMap Candidate Details

Structure:
CMap ID: C05847
Pert ID: BRD-K11071038
Compound Name: ICI-162846
Targets: HRH2
MoA: Histamine receptor antagonist
SMILES: NC(=O)CCCCn1ccc(n1)N=C(/N)NCC(F)(F)F
InchiKey: ALCSGJCIESECFD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121201 BRD-K11071038 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121235 BRD-K11071038 HA1E 3.33 uM 24 h -0.24 -1.0 0.15 0.0 0.0 0.0
121327 BRD-K11071038 PC3 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129250 BRD-K11071038 A375 2.22 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
129281 BRD-K11071038 HELA 2.22 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
129314 BRD-K11071038 HT29 0.25 uM 24 h 0.32 1.32 0.78 -0.38 -1.28 1.45
129347 BRD-K11071038 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129385 BRD-K11071038 YAPC 0.01 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.76
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).