CMap Candidate Details

Structure:
CMap ID: C05850
Pert ID: BRD-K11073688
Compound Name: CPI-1189
Targets: TNF
MoA: Tumor necrosis factor release inhibitor
SMILES: CC(=O)Nc1ccc(cc1)C(=O)NC(C)(C)C
InchiKey: DJKNRCWSXSZACF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121168 BRD-K11073688 A375 1.11 uM 24 h -0.27 -1.12 0.39 0.24 0.84 0.12
121204 BRD-K11073688 A549 1.11 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
121295 BRD-K11073688 MCF??7.00 0.04 uM 24 h 0.2 0.85 0.01 -0.21 -0.71 0.03
121330 BRD-K11073688 PC3 1.11 uM 24 h -0.28 -1.16 0.48 0.0 0.0 0.0
129257 BRD-K11073688 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129283 BRD-K11073688 HELA 0.01 uM 3 h 0.0 0.0 0.0 -0.33 -1.12 0.95
129317 BRD-K11073688 HT29 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129389 BRD-K11073688 YAPC 0.74 uM 24 h 0.22 0.91 0.04 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).