CMap Candidate Details

Structure:
CMap ID: C05860
Pert ID: BRD-K11107424
Compound Name: tiotidine
Targets: HRH2
MoA: Histamine receptor antagonist
SMILES: CNC(=NC#N)NCCSCc1csc(N=C(N)N)n1
InchiKey: YDDXVAXDYKBWDX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4058 BRD-K11107424 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4361 BRD-K11107424 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4647 BRD-K11107424 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4892 BRD-K11107424 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44302 BRD-K11107424 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44520 BRD-K11107424 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44853 BRD-K11107424 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45160 BRD-K11107424 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45426 BRD-K11107424 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45771 BRD-K11107424 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45968 BRD-K11107424 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46288 BRD-K11107424 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100075 BRD-K11107424 U2OS 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.28 1.45
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).