CMap Candidate Details

Structure:
CMap ID: C05864
Pert ID: BRD-K11129031
Compound Name: gemfibrozil
Targets: CYP2C8; LPL; PPARA
MoA: Lipoprotein lipase activator
SMILES: Cc1ccc(C)c(OCCCC(C)(C)C(O)=O)c1
InchiKey: HEMJJKBWTPKOJG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
7623 BRD-K11129031 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8801 BRD-K11129031 VCAP 10 uM 6 h 0.0 0.0 0.0 0.17 0.62 0.0
52794 BRD-K11129031 HEPG2 2.5 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
91397 BRD-K11129031 HUH7 12.5 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
96112 BRD-K11129031 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99001 BRD-K11129031 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99128 BRD-K11129031 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100076 BRD-K11129031 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
121165 BRD-K11129031 A375 0.125 uM 24 h -0.26 -1.1 0.34 -0.37 -1.26 1.35
121236 BRD-K11129031 HA1E 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121328 BRD-K11129031 PC3 3.33 uM 24 h 0.37 1.56 1.48 0.0 0.0 0.0
129268 BRD-K11129031 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129315 BRD-K11129031 HT29 0.01 uM 24 h 0.2 0.85 0.01 -0.19 -0.64 0.01
129348 BRD-K11129031 MCF??7.00 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129386 BRD-K11129031 YAPC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).