CMap Candidate Details

Structure:
CMap ID: C05871
Pert ID: BRD-K11153516
Compound Name: iniparib
Targets: PARP1
MoA: PARP inhibitor
SMILES: NC(=O)c1ccc(I)c(c1)[N+]([O-])=O
InchiKey: MDOJTZQKHMAPBK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
90884 BRD-K11153516 MCF10A 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.36
93639 BRD-K11153516 ASC 10 uM 24 h 0.26 1.09 0.23 -0.21 -0.69 0.02
93696 BRD-K11153516 CD34 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93746 BRD-K11153516 HA1E 0.12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93782 BRD-K11153516 HCC515 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93822 BRD-K11153516 HEK293 3.33 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.5
93913 BRD-K11153516 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
93951 BRD-K11153516 HUVEC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94009 BRD-K11153516 JURKAT 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
94088 BRD-K11153516 NEU 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94169 BRD-K11153516 NPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94219 BRD-K11153516 SHSY5Y 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
94272 BRD-K11153516 SKL 10 uM 24 h 0.0 0.0 0.0 -0.37 -1.24 1.29
94322 BRD-K11153516 THP1 10 uM 24 h 0.0 0.0 0.0 0.24 0.87 0.17
94366 BRD-K11153516 YAPC 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115641 BRD-K11153516 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
115850 BRD-K11153516 HT29 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.48
119906 BRD-K11153516 MCF??7.00 0.002 uM 6 h 0.0 0.0 0.0 -0.28 -0.94 0.37
121207 BRD-K11153516 A549 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121258 BRD-K11153516 HELA 10 uM 24 h 0.0 0.0 0.0 0.36 1.29 1.49
121334 BRD-K11153516 PC3 10 uM 24 h 0.0 0.0 0.0 0.39 1.39 2.17
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).