CMap Candidate Details

Structure:
CMap ID: C05875
Pert ID: BRD-K11163873
Compound Name: phenanthridone
Targets: PARP1
MoA: PARP inhibitor
SMILES: O=c1[nH]c2ccccc2c3ccccc13
InchiKey: RZFVLEJOHSLEFR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4060 BRD-K11163873 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4363 BRD-K11163873 HCC515 10 uM 24 h 0.22 0.92 0.04 0.0 0.0 0.0
4648 BRD-K11163873 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4893 BRD-K11163873 VCAP 10 uM 24 h -0.21 -0.85 0.01 0.0 0.0 0.0
44304 BRD-K11163873 A375 10 uM 6 h 0.24 1.01 0.11 0.28 0.99 0.4
44855 BRD-K11163873 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
45162 BRD-K11163873 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
45428 BRD-K11163873 HT29 10 uM 6 h 0.0 0.0 0.0 -0.46 -1.56 15.65
45772 BRD-K11163873 MCF??7.00 10 uM 6 h -0.2 -0.83 0.0 -0.35 -1.18 1.15
45970 BRD-K11163873 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46290 BRD-K11163873 PHH 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.79 0.11
46605 BRD-K11163873 SKB 10 uM 24 h 0.23 0.97 0.08 -0.25 -0.85 0.19
90553 BRD-K11163873 A549 0.01 uM 24 h -0.24 -1.0 0.14 -0.23 -0.79 0.1
100078 BRD-K11163873 U2OS 25 uM 6 h 0.24 1.02 0.12 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).