CMap Candidate Details

Structure:
CMap ID: C05887
Pert ID: BRD-K11215326
Compound Name: E-7438
Targets: --
MoA: --
SMILES: CCN(C1CCOCC1)c1cc(cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)-c1ccc(CN2CCOCC2)cc1
InchiKey: NSQSAUGJQHDYNO-UHFFFAOYSA-N
Compound Aliases: tazemetostat

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
87295 BRD-K11215326 BJAB 0.5 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87380 BRD-K11215326 HBL1 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87429 BRD-K11215326 K562 0.125 uM 24 h 0.0 0.0 0.0 -0.25 -0.86 0.21
87478 BRD-K11215326 KMS34 10 uM 24 h 0.0 0.0 0.0 0.22 0.78 0.07
87493 BRD-K11215326 MINO 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
87581 BRD-K11215326 NALM6 0.04 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.67
87633 BRD-K11215326 OCILY10 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.78 0.1
87682 BRD-K11215326 OCILY19 2.22 uM 24 h 0.19 0.77 0.0 0.0 0.0 0.0
87733 BRD-K11215326 OCILY3 0.04 uM 24 h 0.23 0.96 0.08 0.3 1.07 0.63
87781 BRD-K11215326 SKMEL5 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.38
87797 BRD-K11215326 THP1 2.22 uM 24 h 0.0 0.0 0.0 -0.25 -0.86 0.2
87840 BRD-K11215326 TMD8 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96217 BRD-K11215326 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96292 BRD-K11215326 U2OS 0.37 uM 24 h 0.0 0.0 0.0 -0.34 -1.13 1.0
96833 BRD-K11215326 A375 10 uM 24 h 0.0 0.0 0.0 0.2 0.71 0.02
96910 BRD-K11215326 PC3 10 uM 24 h -0.24 -1.0 0.14 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).