CMap Candidate Details

Structure:
CMap ID: C00595
Pert ID: BRD-A23683907
Compound Name: NAS-181
Targets: HTR1B
MoA: Serotonin receptor antagonist
SMILES: C(Oc1cccc2C=C(CN3CCOCC3)COc12)C4CNCCO4
InchiKey: RTKDBEOSPDFLGD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4008 BRD-A23683907 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4284 BRD-A23683907 HCC515 10 uM 24 h -0.27 -1.14 0.42 -0.4 -1.34 1.85
4610 BRD-A23683907 PC3 10 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
4984 BRD-A23683907 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37051 BRD-A23683907 A375 10 uM 6 h -0.21 -0.86 0.01 0.0 0.0 0.0
37219 BRD-A23683907 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37459 BRD-A23683907 ASC 10 uM 24 h 0.29 1.21 0.47 0.0 0.0 0.0
37990 BRD-A23683907 HT29 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.04 0.67
38135 BRD-A23683907 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38309 BRD-A23683907 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38611 BRD-A23683907 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38834 BRD-A23683907 SKB 10 uM 24 h -0.22 -0.9 0.05 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).