CMap Candidate Details

Structure:
CMap ID: C05950
Pert ID: BRD-K11433652
Compound Name: aspirin
Targets: PTGS1; PTGS2; TP53
MoA: Cyclooxygenase inhibitor
SMILES: CC(=O)Oc1ccccc1C(O)=O
InchiKey: BSYNRYMUTXBXSQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
50340 BRD-K11433652 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
51010 BRD-K11433652 VCAP 10 uM 24 h -0.16 -0.68 0.0 0.22 0.78 0.07
52588 BRD-K11433652 A549 6.66 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
52897 BRD-K11433652 HEPG2 40 uM 24 h 0.0 0.0 0.0 -0.28 -0.93 0.34
53100 BRD-K11433652 MCF10A 100 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90795 BRD-K11433652 HPTEC 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91306 BRD-K11433652 HUH7 20 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
121171 BRD-K11433652 A375 0.04 uM 24 h -0.25 -1.06 0.25 0.0 0.0 0.0
121273 BRD-K11433652 HELA 10 uM 3 h 0.19 0.8 0.0 0.0 0.0 0.0
121298 BRD-K11433652 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129259 BRD-K11433652 HA1E 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129319 BRD-K11433652 HT29 0.08 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.73
129359 BRD-K11433652 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129392 BRD-K11433652 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).