CMap Candidate Details

Structure:
CMap ID: C05981
Pert ID: BRD-K11540476
Compound Name: EMF-BCA1-64
Targets: STAT1; CASP3
MoA: Caspase inhibitor
SMILES: C[C@@H](CO)N1C[C@@H](C)[C@H](CN(C)S(=O)(=O)c2ccc3OCCOc3c2)Oc4c(NC(=O)Nc5cccc6ccccc56)cccc4C1=O
InchiKey: YDFFDCBBGWXONN-MODXFSQWSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
19602 BRD-K11540476 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21525 BRD-K11540476 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32354 BRD-K11540476 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
32945 BRD-K11540476 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
90813 BRD-K11540476 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96180 BRD-K11540476 A549 3.33 uM 24 h 0.0 0.0 0.0 0.26 0.93 0.26
96246 BRD-K11540476 U2OS 0.37 uM 24 h 0.0 0.0 0.0 -0.2 -0.69 0.02
118412 BRD-K11540476 A375 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.22 1.24
118522 BRD-K11540476 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118567 BRD-K11540476 HEPG2 10 uM 24 h -0.19 -0.79 0.0 0.0 0.0 0.0
118605 BRD-K11540476 HT29 3.33 uM 24 h 0.0 0.0 0.0 -0.25 -0.83 0.17
118638 BRD-K11540476 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118672 BRD-K11540476 PC3 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).