CMap Candidate Details

Structure:
CMap ID: C00006
Pert ID: BRD-A00147595
Compound Name: balaglitazone
Targets: PPARG
MoA: Insulin sensitizer; PPAR receptor partial agonist
SMILES: Cn1c(COc2ccc(CC3SC(=O)NC3=O)cc2)nc2ccccc2c1=O
InchiKey: IETKPTYAGKZLKY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
122851 BRD-A00147595 HA1E 0.04 uM 24 h 0.24 1.02 0.12 0.0 0.0 0.0
122874 BRD-A00147595 HEK293 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122958 BRD-A00147595 HT29 0.37 uM 24 h 0.0 0.0 0.0 -0.33 -1.12 0.96
122999 BRD-A00147595 JURKAT 1.11 uM 24 h -0.33 -1.39 1.09 0.0 0.0 0.0
123051 BRD-A00147595 MCF10A 10 uM 24 h -0.19 -0.8 0.0 -0.31 -1.04 0.68
123069 BRD-A00147595 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123088 BRD-A00147595 MDAMB231 3.33 uM 24 h 0.32 1.35 0.96 0.34 1.21 1.13
123140 BRD-A00147595 PC3 10 uM 24 h -0.28 -1.17 0.49 -0.41 -1.4 2.02
123160 BRD-A00147595 THP1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131197 BRD-A00147595 A375 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131226 BRD-A00147595 A549 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131296 BRD-A00147595 HELA 0.03 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.35
131336 BRD-A00147595 HUVEC 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131480 BRD-A00147595 YAPC 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).