CMap Candidate Details

Structure:
CMap ID: C06018
Pert ID: BRD-K11630072
Compound Name: carmofur
Targets: TYMS
MoA: Thymidylate synthase inhibitor
SMILES: CCCCCCNC(=O)n1cc(F)c(=O)[nH]c1=O
InchiKey: AOCCBINRVIKJHY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24409 BRD-K11630072 A375 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.93 0.35
24555 BRD-K11630072 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24749 BRD-K11630072 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24871 BRD-K11630072 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25005 BRD-K11630072 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25143 BRD-K11630072 PC3 10 uM 24 h 0.0 0.0 0.0 -0.41 -1.37 2.02
25328 BRD-K11630072 VCAP 10 uM 24 h -0.28 -1.15 0.44 -0.31 -1.05 0.7
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).