CMap Candidate Details

Structure:
CMap ID: C06022
Pert ID: BRD-K11634954
Compound Name: GBR-13069
Targets: SLC6A3
MoA: Dopamine uptake inhibitor
SMILES: Fc1ccc(cc1)C(OCCN2CCN(CC=Cc3ccccc3)CC2)c4ccc(F)cc4
InchiKey: DASHZBBQOARCMQ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1545 BRD-K11634954 HA1E 10 uM 24 h 0.17 0.72 0.0 0.0 0.0 0.0
2080 BRD-K11634954 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2221 BRD-K11634954 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2710 BRD-K11634954 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41723 BRD-K11634954 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41910 BRD-K11634954 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42295 BRD-K11634954 ASC 10 uM 24 h 0.26 1.09 0.23 0.0 0.0 0.0
42628 BRD-K11634954 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42931 BRD-K11634954 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43293 BRD-K11634954 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.23 0.81 0.09
43488 BRD-K11634954 NPC 10 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
43792 BRD-K11634954 PHH 10 uM 24 h 0.27 1.14 0.31 0.0 0.0 0.0
44069 BRD-K11634954 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100081 BRD-K11634954 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).