CMap Candidate Details

Structure:
CMap ID: C06081
Pert ID: BRD-K11801786
Compound Name: trimidox
Targets: RRM1
MoA: Ribonucleotide reductase inhibitor
SMILES: ONC(=N)c1cc(O)c(O)c(O)c1
InchiKey: MSLJYSGFUMYUDX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49813 BRD-K11801786 A375 10 uM 6 h 0.19 0.81 0.0 0.0 0.0 0.0
50156 BRD-K11801786 HA1E 10 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.33
50342 BRD-K11801786 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50507 BRD-K11801786 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50738 BRD-K11801786 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50827 BRD-K11801786 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51012 BRD-K11801786 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96114 BRD-K11801786 A549 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.11
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).