CMap Candidate Details

Structure:
CMap ID: C00609
Pert ID: BRD-A24191444
Compound Name: ifenprodil
Targets: GRIN1; GRIN2B
MoA: Glutamate receptor antagonist; Adrenergic receptor antagonist
SMILES: CC(C(O)c1ccc(O)cc1)N1CCC(Cc2ccccc2)CC1
InchiKey: UYNVMODNBIQBMV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24520 BRD-A24191444 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25282 BRD-A24191444 VCAP 10 uM 24 h -0.27 -1.11 0.37 -0.28 -0.94 0.37
91009 BRD-A24191444 HUH7 10 uM 72 h 0.23 0.96 0.07 0.0 0.0 0.0
121378 BRD-A24191444 A375 10 uM 24 h -0.24 -0.98 0.12 0.0 0.0 0.0
121451 BRD-A24191444 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121490 BRD-A24191444 PC3 10 uM 24 h 0.0 0.0 0.0 0.37 1.3 1.49
121541 BRD-A24191444 YAPC 3.33 uM 24 h 0.28 1.15 0.33 -0.27 -0.92 0.32
129454 BRD-A24191444 HA1E 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129476 BRD-A24191444 HELA 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129538 BRD-A24191444 MCF??7.00 0.74 uM 24 h 0.18 0.76 0.0 -0.26 -0.88 0.25
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).