CMap Candidate Details

Structure:
CMap ID: C06157
Pert ID: BRD-K12079898
Compound Name: PD-160170
Targets: NPY1R
MoA: Neuropeptide receptor antagonist
SMILES: CC(C)c1ccccc1S(=O)(=O)c1cc(N)c2ncccc2c1[N+]([O-])=O
InchiKey: YUVNGBZROXQYQH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2837 BRD-K12079898 HA1E 10 uM 24 h 0.25 1.04 0.14 0.0 0.0 0.0
3142 BRD-K12079898 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3467 BRD-K12079898 PC3 10 uM 24 h 0.2 0.84 0.0 0.3 1.05 0.58
3725 BRD-K12079898 VCAP 10 uM 24 h 0.23 0.94 0.06 0.0 0.0 0.0
39092 BRD-K12079898 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39427 BRD-K12079898 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39630 BRD-K12079898 ASC 10 uM 24 h 0.25 1.04 0.14 0.0 0.0 0.0
39947 BRD-K12079898 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40228 BRD-K12079898 HT29 10 uM 6 h 0.0 0.0 0.0 -0.4 -1.35 2.01
40452 BRD-K12079898 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40753 BRD-K12079898 NEU 10 uM 24 h -0.32 -1.32 0.84 -0.27 -0.91 0.29
41053 BRD-K12079898 NPC 10 uM 24 h 0.22 0.91 0.04 -0.36 -1.22 1.24
41382 BRD-K12079898 SKB 10 uM 24 h -0.19 -0.79 0.0 0.27 0.94 0.29
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).