CMap Candidate Details

Structure:
CMap ID: C00616
Pert ID: BRD-A24396574
Compound Name: celastrol
Targets: --
MoA: --
SMILES: CC1C(=O)C(=O)C=C2C1=CC=C3[C@@]2(C)CCC4(C)[C@@H]5C[C@@](C)(CC[C@]5(C)CC[C@]34C)C(=O)O
InchiKey: AQKDBFWJOPNOKZ-TWPXQOCQSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91871 BRD-A24396574 MCF??7.00 10 uM 6 h 0.21 0.86 0.01 -0.39 -1.3 1.58
91904 BRD-A24396574 MDAMB231 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
92407 BRD-A24396574 A375 0.37 uM 24 h 0.27 1.11 0.26 0.0 0.0 0.0
92432 BRD-A24396574 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92462 BRD-A24396574 BT20 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92497 BRD-A24396574 HA1E 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92531 BRD-A24396574 HME1 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92606 BRD-A24396574 HS578T 1.11 uM 3 h -0.22 -0.93 0.07 0.0 0.0 0.0
92628 BRD-A24396574 HT29 1.11 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.73
92666 BRD-A24396574 LNCAP 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92731 BRD-A24396574 MCF10A 0.04 uM 3 h -0.29 -1.22 0.62 -0.27 -0.9 0.28
92804 BRD-A24396574 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92849 BRD-A24396574 SKBR3 10 uM 3 h 0.0 0.0 0.0 -0.25 -0.85 0.19
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).