CMap Candidate Details

Structure:
CMap ID: C00619
Pert ID: BRD-A24429032
Compound Name: BE-2254
Targets: ADRA1A
MoA: Adrenergic receptor antagonist
SMILES: Oc1ccc(CCNCC2CCc3ccccc3C2=O)cc1
InchiKey: PZZOEXPDTYIBPI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1684 BRD-A24429032 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1817 BRD-A24429032 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2325 BRD-A24429032 PC3 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.78 0.1
2677 BRD-A24429032 VCAP 10 uM 6 h -0.26 -1.08 0.29 0.0 0.0 0.0
41654 BRD-A24429032 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42003 BRD-A24429032 A549 10 uM 6 h -0.29 -1.19 0.53 0.0 0.0 0.0
42188 BRD-A24429032 ASC 10 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.18
42533 BRD-A24429032 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.9 0.28
42841 BRD-A24429032 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43255 BRD-A24429032 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43388 BRD-A24429032 NPC 10 uM 24 h 0.2 0.85 0.01 0.27 0.95 0.32
43703 BRD-A24429032 PHH 10 uM 24 h 0.17 0.72 0.0 -0.23 -0.77 0.09
44000 BRD-A24429032 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).