CMap Candidate Details

Structure:
CMap ID: C06193
Pert ID: BRD-K12184470
Compound Name: flunarizine
Targets: CACNA1H; CACNA1G
MoA: Calcium channel blocker
SMILES: Fc1ccc(cc1)C(N2CCN(CC=Cc3ccccc3)CC2)c4ccc(F)cc4
InchiKey: SMANXXCATUTDDT-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1549 BRD-K12184470 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2083 BRD-K12184470 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2540 BRD-K12184470 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41727 BRD-K12184470 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42062 BRD-K12184470 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42300 BRD-K12184470 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42633 BRD-K12184470 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42936 BRD-K12184470 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43492 BRD-K12184470 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
44072 BRD-K12184470 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51372 BRD-K12184470 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.86 0.22
51433 BRD-K12184470 PC3 10 uM 24 h 0.0 0.0 0.0 -0.4 -1.34 1.85
100090 BRD-K12184470 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).