CMap Candidate Details

Structure:
CMap ID: C06199
Pert ID: BRD-K12219985
Compound Name: glipizide
Targets: KCNJ11; ABCC8
MoA: Sulfonylurea
SMILES: Cc1cnc(cn1)C(=O)NCCc1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1
InchiKey: ZJJXGWJIGJFDTL-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4364 BRD-K12219985 HCC515 10 uM 24 h -0.16 -0.67 0.0 -0.37 -1.25 1.35
4894 BRD-K12219985 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37594 BRD-K12219985 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37873 BRD-K12219985 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38429 BRD-K12219985 NPC 10 uM 24 h 0.0 0.0 0.0 0.43 1.54 2.31
38913 BRD-K12219985 SKB 10 uM 24 h 0.0 0.0 0.0 0.32 1.12 0.76
90955 BRD-K12219985 HUH7 8 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
100091 BRD-K12219985 U2OS 12 uM 6 h -0.24 -1.0 0.15 -0.33 -1.11 0.9
122234 BRD-K12219985 A375 0.04 uM 24 h 0.24 0.99 0.1 0.0 0.0 0.0
122277 BRD-K12219985 A549 1.11 uM 24 h -0.24 -0.98 0.13 0.0 0.0 0.0
122291 BRD-K12219985 HA1E 3.33 uM 24 h -0.22 -0.92 0.06 -0.36 -1.21 1.23
122380 BRD-K12219985 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
122456 BRD-K12219985 THP1 10 uM 24 h 0.26 1.1 0.24 -0.31 -1.06 0.73
130609 BRD-K12219985 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.39 1.38 2.16
130650 BRD-K12219985 HELA 0.08 uM 24 h 0.27 1.13 0.29 0.0 0.0 0.0
130690 BRD-K12219985 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130731 BRD-K12219985 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130775 BRD-K12219985 MDAMB231 0.25 uM 24 h 0.0 0.0 0.0 0.38 1.35 1.72
130802 BRD-K12219985 PC3 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
130825 BRD-K12219985 YAPC 0.01 uM 24 h 0.22 0.94 0.05 -0.41 -1.38 2.02
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).