CMap Candidate Details

Structure:
CMap ID: C06259
Pert ID: BRD-K12401458
Compound Name: BRD-K12401458
Targets: S1PR4
MoA: Lysophospholipid receptor agonist
SMILES: COCCN=C1/SC(=C/c2cc(C)n(c2C)-c2ccc(F)cc2F)C(=O)N1C
InchiKey: BKQZKTRCUAWRHT-ZGNGNRKCSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
16212 BRD-K12401458 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
16591 BRD-K12401458 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
16922 BRD-K12401458 HCC515 10 uM 6 h 0.0 0.0 0.0 0.29 1.04 0.56
17247 BRD-K12401458 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.63
17589 BRD-K12401458 HT29 10 uM 6 h -0.27 -1.12 0.38 -0.32 -1.08 0.8
17913 BRD-K12401458 MCF??7.00 10 uM 24 h -0.27 -1.11 0.37 0.0 0.0 0.0
18409 BRD-K12401458 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
18706 BRD-K12401458 VCAP 10 uM 6 h 0.23 0.96 0.08 0.26 0.91 0.23
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).