CMap Candidate Details

Structure:
CMap ID: C00629
Pert ID: BRD-A24891640
Compound Name: nimodipine
Targets: NR3C2; CACNA1C; CACNA1D; CACNA1F; CACNA1S
MoA: Calcium channel blocker
SMILES: COCCOC(=O)C1C(C(=C(C)N=C1C)C(=O)OC(C)C)c2cccc(c2)[N+](=O)[O-]
InchiKey: BAARDDGSQHXDDB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
22052 BRD-A24891640 A375 10 uM 6 h 0.22 0.92 0.04 0.2 0.71 0.02
22378 BRD-A24891640 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22638 BRD-A24891640 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22918 BRD-A24891640 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23224 BRD-A24891640 HT29 10 uM 6 h -0.21 -0.89 0.03 -0.34 -1.16 1.1
23505 BRD-A24891640 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.81 0.13
23784 BRD-A24891640 PC3 10 uM 24 h -0.17 -0.72 0.0 0.0 0.0 0.0
24077 BRD-A24891640 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).