CMap Candidate Details

Structure:
CMap ID: C06293
Pert ID: BRD-K12513978
Compound Name: fenbufen
Targets: PTGS1; PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: OC(=O)CCC(=O)c1ccc(cc1)-c1ccccc1
InchiKey: ZPAKPRAICRBAOD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5185 BRD-K12513978 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5301 BRD-K12513978 HA1E 10 uM 24 h -0.27 -1.12 0.38 0.0 0.0 0.0
5579 BRD-K12513978 HCC515 10 uM 24 h 0.0 0.0 0.0 0.23 0.82 0.1
5883 BRD-K12513978 HEPG2 10 uM 6 h -0.27 -1.13 0.41 0.0 0.0 0.0
6261 BRD-K12513978 PC3 10 uM 6 h 0.0 0.0 0.0 -0.3 -1.02 0.62
6343 BRD-K12513978 VCAP 10 uM 24 h -0.19 -0.77 0.0 0.0 0.0 0.0
39428 BRD-K12513978 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39631 BRD-K12513978 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40229 BRD-K12513978 HT29 10 uM 6 h -0.22 -0.9 0.04 -0.27 -0.91 0.31
40754 BRD-K12513978 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41054 BRD-K12513978 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41383 BRD-K12513978 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
51347 BRD-K12513978 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.21 1.24
91317 BRD-K12513978 HUH7 12.5 uM 72 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).