CMap Candidate Details

Structure:
CMap ID: C00063
Pert ID: BRD-A02367930
Compound Name: BRD-A02367930
Targets: --
MoA: --
SMILES: C[C@]12CCC3C(CCc4cc(O)ccc34)C1CC[C@@]2(O)C#C
InchiKey: BFPYWIDHMRZLRN-OQPPHWFISA-N
Compound Aliases: ethinyl-estradiol

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8538 BRD-A02367930 VCAP 10 uM 24 h 0.3 1.23 0.5 -0.26 -0.88 0.25
95505 BRD-A02367930 A549 1.11 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
95616 BRD-A02367930 U2OS 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.12
96504 BRD-A02367930 PC3 10 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
122836 BRD-A02367930 A375 10 uM 24 h 0.18 0.76 0.0 -0.34 -1.15 1.06
122903 BRD-A02367930 HEK293 10 uM 24 h -0.19 -0.81 0.0 0.0 0.0 0.0
122979 BRD-A02367930 HT29 10 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
123028 BRD-A02367930 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123118 BRD-A02367930 MDAMB231 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123190 BRD-A02367930 THP1 10 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
131283 BRD-A02367930 HA1E 0.03 uM 24 h 0.27 1.11 0.26 0.0 0.0 0.0
131309 BRD-A02367930 HELA 2.22 uM 24 h 0.22 0.92 0.04 -0.26 -0.87 0.24
131366 BRD-A02367930 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131404 BRD-A02367930 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131442 BRD-A02367930 MCF??7.00 2.22 uM 24 h 0.33 1.39 1.02 -0.28 -0.94 0.38
131503 BRD-A02367930 YAPC 2.22 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.4
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).