CMap Candidate Details

Structure:
CMap ID: C00635
Pert ID: BRD-A25143711
Compound Name: hydrocortisone-valerate
Targets: NR3C1
MoA: Corticosteroid agonist; Glucocorticoid receptor agonist
SMILES: CCCCC(=O)O[C@@]1(CCC2C3CCC4=CC(=O)CC[C@]4(C)C3[C@@H](O)C[C@]12C)C(=O)CO
InchiKey: FZCHYNWYXKICIO-BXLKFAEVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4160 BRD-A25143711 HA1E 10 uM 6 h 0.27 1.11 0.26 -0.32 -1.07 0.76
4285 BRD-A25143711 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.28 1.45
4611 BRD-A25143711 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4841 BRD-A25143711 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
37052 BRD-A25143711 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37330 BRD-A25143711 A549 10 uM 6 h 0.0 0.0 0.0 0.37 1.31 1.59
37460 BRD-A25143711 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37795 BRD-A25143711 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.33 1.18 1.01
38241 BRD-A25143711 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38310 BRD-A25143711 NPC 10 uM 24 h 0.0 0.0 0.0 0.29 1.01 0.45
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).