CMap Candidate Details

Structure:
CMap ID: C00646
Pert ID: BRD-A25619068
Compound Name: fadrozole
Targets: CYP19A1
MoA: Aromatase inhibitor
SMILES: N#Cc1ccc(cc1)C1CCCc2cncn12
InchiKey: CLPFFLWZZBQMAO-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
51374 BRD-A25619068 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
95309 BRD-A25619068 A549 4 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
95471 BRD-A25619068 U2OS 0.05 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.48
120875 BRD-A25619068 A375 1.11 uM 24 h 0.2 0.85 0.01 0.2 0.71 0.02
120973 BRD-A25619068 HEK293 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121130 BRD-A25619068 YAPC 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129143 BRD-A25619068 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129172 BRD-A25619068 HELA 0.08 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
129204 BRD-A25619068 HT29 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129232 BRD-A25619068 PC3 0.25 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).